Premier League predictions: Man City stuff Spurs, Liverpool hammer Norwich

Tottenham pulled off a smash-and-grab win on opening day, but City's march towards retaining the Premier League title since has been relentless

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  SATURDAY: 4.30pm (UAE) - West Ham United v Newcastle United: Newcastle are on a roll; unbeaten in their last five matches including three wins on the spin, Eddie Howe's team look like they may pull off the great escape. Kieran Trippier's injury is a huge blow, but the Magpies should be good for at least a point against an inconsistent West Ham. Prediction: Newcastle 1, West Ham 1. Getty Images

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  Arsenal v Brentford, 7pm: Brentford announced their arrival to the big time by beating the Gunners 2-0 on their Premier League debut in August. The honeymoon period is over for Thomas Frank's side, though, with four defeats in their last five. Arsenal are four points off fourth with games in hand on all those above them. They need to inflict revenge to aid their Champions League qualification hopes. Prediction: Arsenal 3, Brentford 1. Getty Images

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  Aston Villa v Watford, 7pm: Defeat to Newcastle last time out left Villa manager Steven Gerrard raging, and he will be looking for a vast improvement against a Watford side struggling to survive. Hard to see the Hornets picking up points on the road. Prediction: Aston Villa 2, Watford 0. Getty Images

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  Brighton & Hove Albion v Burnley, 7pm: Draw specialists Brighton followed up victory over Watford with a defeat at Manchester United. The Seagulls will be without talismanic captain Lewis Dunk, who saw red in the 2-0 defeat at Old Trafford, which bottom-club Burnley will hope to capitalise on. Prediction: Brighton 0, Burnley 1. Getty Images

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  Crystal Palace v Chelsea, 7pm: Chelsea return from their trip to Abu Dhabi where they were crowned world champions with a tough trip across town to Crystal Palace. The Blues have lost ground on leaders Manchester City, and are unlikely to get much change out of an obdurate Palace. Prediction: Palace 1, Chelsea 1. Getty Images

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  Liverpool v Norwich City, 7pm: Liverpool pulled off a sensational win in midweek at Inter Milan and ride a four-game win streak into this Premier League encounter. Norwich tend to suffer more than most against the league's big hitters and Saturday's trip to Anfield will be no different. Prediction: Liverpool 4, Norwich 0. Getty Images

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  Southampton v Everton, 7pm: A comeback win over Tottenham sandwiched draws against Manchester United and Man City as Southampton have started to claw their way back into the top half of the table. Everton's win over Leeds last time out was their first under Frank Lampard and halted a run of six leagues games without a win. Prediction: Southampton 2, Everton 1. Getty Images

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  Manchester City v Tottenham Hotspur, 9.30pm. Spurs rode their luck to pull off a smash-and-grab victory when City visited the Tottenham Hotspur Stadium on the opening day to top the league season, but fortunes have been reversed since. City top the table by nine points and their journey to another Premier League title will only continue at the Etihad. Prediction: Man City 3, Spurs 1. Getty Images

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  SUNDAY: Leeds United v Manchester United, 6pm: Rumours of a dressing-room power struggle paint a picture of a Manchester United side at odds with itself. Cristiano Ronaldo's return has been portrayed as underwhelming and troublesome, but no one else in the squad has come close to his nine Premier League goals this season. Leeds have a golden chance to test United's unity. Prediction: Leeds 1, Manchester United 1. Getty Images

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  Wolves v Leicester City, 8.30pm: Wolves have aligned frugality at the back with potency in attack of late as they look to gatecrash the top four. Leicester's win over Randers on Thursday will provide a shot in the arm to the Foxes' confidence. Prediction: Wolves 2, Leicester 0. Getty Images

Leaders Manchester City will look to maintain their winning momentum as they seek to retain the Premier League crown when Tottenham visit the Etihad Stadium on Saturday.

Spurs pulled off a smash-and-grab against City on the opening day, but City's march towards a sixth Premier League title under Abu Dhabi ownership since has been relentless.

City are nine points clear of Liverpool, who will look to follow up Wednesday's victory over Inter Milan by putting struggling Norwich City to the sword.

Saturday's fixtures kick off with Newcastle United in the almost unheard of position of looking for a fourth Premier League win on the spin when they travel to West Ham United.

News of Kieran Trippier's foot injury will have come as a huge blow for Newcastle manager Eddie Howe. The England defender has been responsible for an uptick in results since his January move from Atletico Madrid.

Arsenal will look to avenge their opening night defeat to promoted Brentford when the Bees travel to the Emirates Stadium; Aston Villa entertain relegation-haunted Watford, bottom-club Burnley travel to Brighton, Southampton welcome Everton and newly-minted Fifa Club World Cup champions Chelsea have a tough trip across town to Crystal Palace.

On Sunday, Manchester united will look to put reports of a rift between Harry Maguire and Cristiano Ronaldo behind them with victory at Leeds United while Wolves v Leicester closes out this matchday.

To see our Premier League predictions, scroll through the photo gallery above.