Chelsea v Tottenham (8.30pm): Thomas Tuchel has blamed Chelsea's current blip in form - the Blues are without a win in four games - on tiredness, but it still feels surprising considering the strength in depth of his squad. The Blues need striker Romelu Lukaku to rediscover his scoring touch - and fast. Prediction: Chelsea 1 Spurs 0. AP
FRIDAY - Watford v Norwich (midnight): Another huge game in the relegation dogfight. Watford were given a boost last week when they snatched a deserved late leveler at fellow strugglers Newcastle, ending their six-game losing streak. Norwich secured their first points - and scored their first goals - since November by beating Everton at Carrow Road. Prediction: Watford 1 Norwich 1. PA
SATURDAY - Everton v Aston Villa (4.30pm): The Rafa Benitez gamble at Everton failed and the Spaniard was axed just six months into the job. Toffees hero Duncan Ferguson is back in temporary charge and first up is Villa, with Liverpool legend Steven Gerrard at the helm and former Red Philippe Coutinho poised for his first start. Prediction: Everton 1 Villa 2. PA
Brentford v Wolves (7pm): A rare goals rush from Bruno Lage's team last week as they defeated Southampton and scored three goals in a league game for only the second time this season. They sit eighth in the table and could potentially move into the top six by winning here. Prediction: Brentford 0 Wolves 2. AP
Leeds v Newcastle (7pm): An excellent win at top-four West Ham put some much-needed daylight between Leeds and the bottom three. Now nine points clear of the drop zone and taking on a Newcastle side still with just one win all season, and manager Eddie Howe struggling to turn around fortunes and form at the Tyneside club. Prediction: Leeds 3 Newcastle 2. Reuters
Manchester United v West Ham (7pm): Hammers manager David Moyes has the chance to stick the boot into his former club here. Currently fourth in the table and looking down on United, Moyes will be hoping for a reaction from his side after West Ham lost at home to Leeds last week. Prediction: Man United 1 West Ham 2. AFP
Southampton v Manchester City (9.30pm): There's just no stopping relentless City at the moment, who are hurtling to another Premier title at a ferocious pace. Saturday's victory over Chelsea was their 12th successive league win and they currently sit 11 points ahead of second-placed Liverpool, albeit having played one game more. Prediction: Southampton 0 City 2. PA
SUNDAY - Arsenal v Burnley (6pm): Both of these teams have seen recent fixtures postponed by Covid outbreaks, so it remains to be seen whether this one will go ahead. If it does, it would be a monumental surprise if the Gunners do not run out comfortable winners at the Emirates against bottom club Burnley. Prediction: Arsenal 4 Burnley 1. Getty
Crystal Palace v Liverpool (6pm): Liverpool showed in last week's 3-1 victory over Brentford that they still have goals in their team even with top scorers Mohamed Salah and Sadio Mane away on Afcon duty. Palace are tricky, if inconsistent opposition this season and it's Liverpool by an odd goal here. Prediction: Palace 1 Liverpool 2. AFP
Leicester v Brighton (6pm): Leicester are desperately trying to gain momentum as they look to push themselves back into contention for the European places. Brighton would have felt like a foregone conclusion last season but Graham Potter's ninth-placed side are above the Foxes in the table for good reason. Prediction: Leicester 1 Brighton 1. AP
Chelsea v Tottenham (8.30pm): Thomas Tuchel has blamed Chelsea's current blip in form - the Blues are without a win in four games - on tiredness, but it still feels surprising considering the strength in depth of his squad. The Blues need striker Romelu Lukaku to rediscover his scoring touch - and fast. Prediction: Chelsea 1 Spurs 0. AP
FRIDAY - Watford v Norwich (midnight): Another huge game in the relegation dogfight. Watford were given a boost last week when they snatched a deserved late leveler at fellow strugglers Newcastle, ending their six-game losing streak. Norwich secured their first points - and scored their first goals - since November by beating Everton at Carrow Road. Prediction: Watford 1 Norwich 1. PA
SATURDAY - Everton v Aston Villa (4.30pm): The Rafa Benitez gamble at Everton failed and the Spaniard was axed just six months into the job. Toffees hero Duncan Ferguson is back in temporary charge and first up is Villa, with Liverpool legend Steven Gerrard at the helm and former Red Philippe Coutinho poised for his first start. Prediction: Everton 1 Villa 2. PA
Brentford v Wolves (7pm): A rare goals rush from Bruno Lage's team last week as they defeated Southampton and scored three goals in a league game for only the second time this season. They sit eighth in the table and could potentially move into the top six by winning here. Prediction: Brentford 0 Wolves 2. AP
Leeds v Newcastle (7pm): An excellent win at top-four West Ham put some much-needed daylight between Leeds and the bottom three. Now nine points clear of the drop zone and taking on a Newcastle side still with just one win all season, and manager Eddie Howe struggling to turn around fortunes and form at the Tyneside club. Prediction: Leeds 3 Newcastle 2. Reuters
Manchester United v West Ham (7pm): Hammers manager David Moyes has the chance to stick the boot into his former club here. Currently fourth in the table and looking down on United, Moyes will be hoping for a reaction from his side after West Ham lost at home to Leeds last week. Prediction: Man United 1 West Ham 2. AFP
Southampton v Manchester City (9.30pm): There's just no stopping relentless City at the moment, who are hurtling to another Premier title at a ferocious pace. Saturday's victory over Chelsea was their 12th successive league win and they currently sit 11 points ahead of second-placed Liverpool, albeit having played one game more. Prediction: Southampton 0 City 2. PA
SUNDAY - Arsenal v Burnley (6pm): Both of these teams have seen recent fixtures postponed by Covid outbreaks, so it remains to be seen whether this one will go ahead. If it does, it would be a monumental surprise if the Gunners do not run out comfortable winners at the Emirates against bottom club Burnley. Prediction: Arsenal 4 Burnley 1. Getty
Crystal Palace v Liverpool (6pm): Liverpool showed in last week's 3-1 victory over Brentford that they still have goals in their team even with top scorers Mohamed Salah and Sadio Mane away on Afcon duty. Palace are tricky, if inconsistent opposition this season and it's Liverpool by an odd goal here. Prediction: Palace 1 Liverpool 2. AFP
Leicester v Brighton (6pm): Leicester are desperately trying to gain momentum as they look to push themselves back into contention for the European places. Brighton would have felt like a foregone conclusion last season but Graham Potter's ninth-placed side are above the Foxes in the table for good reason. Prediction: Leicester 1 Brighton 1. AP
Chelsea v Tottenham (8.30pm): Thomas Tuchel has blamed Chelsea's current blip in form - the Blues are without a win in four games - on tiredness, but it still feels surprising considering the strength in depth of his squad. The Blues need striker Romelu Lukaku to rediscover his scoring touch - and fast. Prediction: Chelsea 1 Spurs 0. AP
