Tottenham v Arsenal (8.30pm): An intriguing North London derby at the Tottenham Hotspur Stadium. Sixth-placed Spurs are two points and two places behind their rivals - but have two games in hand. Arsenal were unlucky to see their four-game win streak come to an end against Manchester City. Prediction: Spurs 1 Arsenal 0. AFP
FRIDAY - Brighton v Crystal Palace (midnight): Brighton are sitting comfortably in the top half after taking seven points out of a possible nine and are looking up towards European places rather than down at the relegation trapdoor. These two teams have 17 draws between them this season with another on the way. Brighton 1 Palace 1. Reuters
SATURDAY - Manchester City v Chelsea (4.30pm): A top-of-the-table clash, although only one is showing the form of champions. City have won 11 in a row and are 10 points clear of second-placed Chelsea. Thomas Tuchel's side, though, have managed just one win in five. Prediction: City 1 Chelsea 0. PA
Burnley v Leicester: Postponed. Getty
Newcastle v Watford (7pm): A relegation six-pointer. The Magpies were knocked out of the FA Cup at home to Cambridge last week, have won once all season but have at least been given a boost by the arrival of striker Chris Wood. Watford have lost six on the spin and appear in freefall. Prediction: Newcastle 2 Watford 1. PA
Norwich v Everton (7pm): Norwich are rock bottom, have lost give games in a row without scoring and conceded 14 ... things are looking grim for the hapless Canaries. It is also fair to say Rafa Benitez is finding life tricky at Everton, where he has won just once since September. Prediction: Norwich 0 Everton 2. Getty
Wolves v Southampton (7pm): Bruno Lage's Wolves continue to struggle to score but are very hard to break down. Remarkably, only bottom side Norwich have scored less than their 14 goals, while table-topping Manchester City are the one club to have conceded less than their 14. Prediction: Wolves 1 Southampton 0. Getty
Aston Villa v Manchester United (9.30pm): These two teams met in the FA Cup just five days earlier with United edging the game 1-0, although Villa had two goals disallowed - one debatable, to say the least. Despite losing just once under interim manager Ralf Rangnick, United look far from convincing. Prediction: Villa 2 United 1. EPA
SUNDAY - Liverpool v Brentford (6pm): Without a win in three games, and Sadio Mane and Mohamed Salah away on Africa Cup of Nations duty, but this game still represents a chance for Liverpool to get their faltering title hopes back on track. Brentford looked woeful in their 4-1 thrashing at Southampton on Tuesday. Prediction: Liverpool 3 Brentford 0. EPA
West Ham v Leeds (6pm): The Hammers seem to have recovered from their recent stumble, winning two on the trot to leave them just a point and one place outside the top four. Marcelo Bielsa said his Leeds side took a "step forward" in beating Burnley last time out but still sit just two places outside the drop zone. Prediction: West Ham 2 Leeds 1. Reuters
Tottenham v Arsenal (8.30pm): An intriguing North London derby at the Tottenham Hotspur Stadium. Sixth-placed Spurs are two points and two places behind their rivals - but have two games in hand. Arsenal were unlucky to see their four-game win streak come to an end against Manchester City. Prediction: Spurs 1 Arsenal 0. AFP
FRIDAY - Brighton v Crystal Palace (midnight): Brighton are sitting comfortably in the top half after taking seven points out of a possible nine and are looking up towards European places rather than down at the relegation trapdoor. These two teams have 17 draws between them this season with another on the way. Brighton 1 Palace 1. Reuters
SATURDAY - Manchester City v Chelsea (4.30pm): A top-of-the-table clash, although only one is showing the form of champions. City have won 11 in a row and are 10 points clear of second-placed Chelsea. Thomas Tuchel's side, though, have managed just one win in five. Prediction: City 1 Chelsea 0. PA
Burnley v Leicester: Postponed. Getty
Newcastle v Watford (7pm): A relegation six-pointer. The Magpies were knocked out of the FA Cup at home to Cambridge last week, have won once all season but have at least been given a boost by the arrival of striker Chris Wood. Watford have lost six on the spin and appear in freefall. Prediction: Newcastle 2 Watford 1. PA
Norwich v Everton (7pm): Norwich are rock bottom, have lost give games in a row without scoring and conceded 14 ... things are looking grim for the hapless Canaries. It is also fair to say Rafa Benitez is finding life tricky at Everton, where he has won just once since September. Prediction: Norwich 0 Everton 2. Getty
Wolves v Southampton (7pm): Bruno Lage's Wolves continue to struggle to score but are very hard to break down. Remarkably, only bottom side Norwich have scored less than their 14 goals, while table-topping Manchester City are the one club to have conceded less than their 14. Prediction: Wolves 1 Southampton 0. Getty
Aston Villa v Manchester United (9.30pm): These two teams met in the FA Cup just five days earlier with United edging the game 1-0, although Villa had two goals disallowed - one debatable, to say the least. Despite losing just once under interim manager Ralf Rangnick, United look far from convincing. Prediction: Villa 2 United 1. EPA
SUNDAY - Liverpool v Brentford (6pm): Without a win in three games, and Sadio Mane and Mohamed Salah away on Africa Cup of Nations duty, but this game still represents a chance for Liverpool to get their faltering title hopes back on track. Brentford looked woeful in their 4-1 thrashing at Southampton on Tuesday. Prediction: Liverpool 3 Brentford 0. EPA
West Ham v Leeds (6pm): The Hammers seem to have recovered from their recent stumble, winning two on the trot to leave them just a point and one place outside the top four. Marcelo Bielsa said his Leeds side took a "step forward" in beating Burnley last time out but still sit just two places outside the drop zone. Prediction: West Ham 2 Leeds 1. Reuters
Tottenham v Arsenal (8.30pm): An intriguing North London derby at the Tottenham Hotspur Stadium. Sixth-placed Spurs are two points and two places behind their rivals - but have two games in hand. Arsenal were unlucky to see their four-game win streak come to an end against Manchester City. Prediction: Spurs 1 Arsenal 0. AFP
