Safety alerts were issued on Friday evening in Dubai and Abu Dhabi.
The Ministry of Interior urged people to immediately seek a safe place and stay away from windows, doors and open areas due to missile threats.
"Air defence systems are currently dealing with a missile threat," the ministry wrote on X. "Please remain in a safe place and follow warnings and updates on the official channels."
Another alert saying the situation was currently safe was sent out minutes later in Dubai.
The UAE said it dealt with seven ballistic missiles and 27 drones launched from Iran on Friday.
Since the start of Iran's attacks, the UAE's air defences have dealt with 285 ballistic missiles, 15 cruise missiles, and 1,567 drones, the Ministry of Defence said on social media.
Debris fell on the facade of a building in central Dubai on Friday morning, after an Iranian attack was intercepted.
The Dubai Media Office said no injuries were reported after what it described as a "minor incident", in a message shared at 7.34am.
Residents in Abu Dhabi and Dubai were urged to shelter less than an hour later owing to a potential missile threat from Iran. The Ministry of Interior called on the public to "immediately seek a safe place" in a message sent to mobile phone users shortly after 8.15am.
People were asked to stay away from windows, doors and open areas owing to “potential missile threats”.
The ministry shared a further update at 8.40am stating that the situation was safe. "You may resume your normal activities while continuing to remain cautious," the message said.
The UAE has faced a barrage of missile and drone attacks from Iran since February 28. The UAE said it intercepted 10 ballistic missiles and 26 drones fired from Iran on Thursday.
“The Ministry of Defence affirmed that it remains fully prepared and ready to deal with any threats and will firmly confront any attempts to undermine State security in a manner that ensures the protection of its sovereignty, security and stability, and safeguards its national interests and capabilities,” the ministry said on X.
