The risk of developing 18 cancers increases if people are overweight as young adults, researchers have found.
A heightened risk of a number of different cancers including breast, bowel, kidney and pancreatic have previously been discovered as being linked to excess weight and obesity.
Now being overweight has also been linked to leukaemia, non-Hodgkin lymphoma, and, among never-smokers, to bladder and head and neck cancers in a large new study.
The authors said these cancers have not previously been “considered as obesity-related cancers” and that the impact of obesity on cancer is “likely underestimated”.
In the new study, published in Nature Communications, researchers examined data on more than 2.6 million Spanish adults aged 40 and under who were cancer-free in 2009.
Researchers examined the body mass index scores throughout the lifetime of people involved with the study, saying that previous research investigating the link between weight and cancer has used single BMI scores.
The people in the study were tracked for nine years to see whether they developed cancer.
About 225,396 were diagnosed with cancer during the period studied.
The Spanish researchers found that those who were overweight or obese in early adulthood – aged 40 and under – appeared to have an increased risk of cancer.
Those who were overweight or obese for a longer period also appeared to have a higher risk.
Overall, about 18 cancers were linked to excess weight.
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“Our findings seem to indicate that longer exposures to overweight and obesity (with or without accounting for the degree of overweight and obesity), as well as developing overweight and obesity at younger ages in early adulthood might increase cancer risk,” the authors wrote.
“Our findings support public health strategies for cancer prevention focusing on preventing and reducing early overweight and obesity.”
Heinz Freisling of the International Agency for Research on Cancer and one of the study’s co-leaders said: “The results of our study support a re-evaluation of the cancer burden associated with overweight and obesity, which currently is likely underestimated.”
Commenting on the study, Panagiota Mitrou, director of research, policy and innovation at the World Cancer Research Fund, said: “This large study has future public health implications since additional cancers, such as leukaemia and non-Hodgkin lymphoma, have been shown to be linked with overweight and obesity.
“Our own evidence shows that maintaining a healthy weight throughout life is one of the most important things people can do to reduce their cancer risk, and early prevention in adulthood is key.”
