As well as honouring excellence, the Grammy Awards is also known for show-stopping performances by an eclectic array of leading artists. Here are some of the musical highlights to look forward to during the evening.
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Honouring Prince
The performance side of the Grammys is sure to be emotional again this year. Last year’s ceremony featured a memorable tribute to the recently-departed David Bowie by Lady Gaga and Chic-legend Nile Rodgers. This time we can expect a substantial Prince medley, probably featuring Bruno Mars (even though he’s more of a Michael Jackson guy, really).
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Beyoncé
A relatively late addition to the bill, Beyoncé might well show some Prince love, too, as she performed with him back at the 2004 event. And, yes, she is pregnant with twins, but expecting a baby has not stopped Grammy performers in the past. In 2009, for example, M.I.A. took to the stage on her due date.
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A Tribe Called Quest
Last year was intense for legendary hip-hoppers A Tribe Called Quest, who released an acclaimed, Grammy-nominated comeback album, We Got It from Here, but also lost founder member Phife Dawg. The void was set to be filled at the Grammys by emerging rapper Anderson .Paak and Foo Fighters' frontman Dave Grohl, but Grohl pulled out saying that he had been announced prematurely. Watch this space.
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Alicia Keys and Maren Morris
Rap/R&B and country music figure heavily this year, and those worlds collide in one of the ceremony’s highest-profile hookups, as Alicia Keys (pictured) duets with country starlet Maren Morris. The hefty posse of country acts lined up – Keith Urban, Sturgill Simpson, Carrie Underwood, and the band Little Big Town – suggests a cowboy hat-sporting supergroup, who will probably pay tribute to Merle Haggard who died in April.
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Daft Punk and The Weeknd
The most eagerly-awaited performance? Adele, Metallica and John Legend also feature, but the real showstopper is likely to be robot-masked techno wizards Daft Punk teaming up with R&B rebel The Weeknd, in the latest of their fine run of recent collaborations. Given the French duo's insistence on striking visuals, expect the Staples Center to transform into something resembling their cameo in Tron: Legacy.
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History's medical milestones
1799 - First small pox vaccine administered
1846 - First public demonstration of anaesthesia in surgery
1861 - Louis Pasteur published his germ theory which proved that bacteria caused diseases
1895 - Discovery of x-rays
1923 - Heart valve surgery performed successfully for first time
1928 - Alexander Fleming discovers penicillin
1953 - Structure of DNA discovered
1952 - First organ transplant - a kidney - takes place
1954 - Clinical trials of birth control pill
1979 - MRI, or magnetic resonance imaging, scanned used to diagnose illness and injury.
1998 - The first adult live-donor liver transplant is carried out
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